Karl Fischer reagents are used in the analysis of water content in raw material and finished products in food, pharmaceutical, chemicals and oil industries. To address the growing demand of stable Volumetric Karl Fischer reagents, Ours R&D has developed an in-house technology which is suitable for manual and automatic equipment ensuring a consistent factor. We also provide Coulometric Karl Fischer Reagents from Aquamicron, Japan
Karl Fischer titration (Volumetric and Coulometric) is used to analyse moisture content in pharmaceutical, petroleum, cosmetic, chemical and food samples. This method uses Karl Fischer reagents which react quantitatively and selectively with water to measure moisture content. Karl Fischer reagent consists of iodine, sulphur dioxide, a base and a solvent such as alcohol.
I2 + SO2 + 3Base + ROH + H2O ⇒ 2Base . HI + Base . HSO4R
In Volumetric Titration a dehydrating solvent suitable for the sample is placed in a flask after which a titrant is used to remove all the moisture from the solvent. After adding the sample, titration is carried out using a titrant, the titer (mg H2O/ml) of which has previously been determined. The moisture content of the sample is determined from the titration volume (ml) and the end point is detected using the constant-current polarization voltage method.
Made from anhydrous ingredients which give constant and stable factor
| Product Code | Description | Pack Size |
|---|---|---|
| 20805LM500 | Karl Fischer Reagent (Pyridine free) | 500 ml |
| 20805LM250 | Karl Fischer Reagent (Pyridine free) | 2x250 ml |
Moisture testing is simple and reliable with Karl Fischer Reagent. The formulation uses anhydrous ingredients to maintain a stable factor and reduce the need for frequent calibration. You get consistent and accurate results across various sample types.
It supports moisture estimation from 200 ppm to percentage level in inorganic and organic salts and solvents. The unique composition gives optimal viscosity for both manual and automated titrators. It also helps you achieve faster titration speed.
| Product Code | Description | Titre Range | Pack Size |
|---|---|---|---|
| SSZ10M | AOUAMICRON SSZ10M | 0.7–1.2 mg H₂O/ml | 500 ml |
| SSZ30M | AOUAMICRON SSZ30M | 2.5–3.5 mg H₂O/ml | 500 ml |
These solvents are designed for residual solvent analysis in excipients, APIs, and drug products.
Each batch goes through a controlled GC-HS setup. Organic volatile impurities are monitored carefully. A multi-step purification process helps meet regulatory requirements. Inert gas blanketing protects against oxidation and ensures batch stability. Small packs reduce contamination during lab analysis.
GC grade solvents are used in impurity profiling, pesticide residue analysis, and polymer testing. Each solvent undergoes controlled analysis for hydrocarbon and halogenated impurities using GC/FID and GC/ECD.
IR and GC methods are used to characterize purity. These solvents match the quality needed for reference standards in GC applications. They also support toxic contaminant testing in environmental and specialty chemical samples.
HPLC-grade solvents meet strict laboratory and safety standards. Solvents are filtered through 0.2 micron filters to protect columns and instruments. Peroxide levels are checked in sensitive solvents. You also get options with or without stabilizers.
Teflon wads are used to stop plasticizer leaching from bottle caps.
With Coulometric titration, the sample is added to an electrolytic solution, the main constituents of which are iodide ions, sulphur dioxide, a base and a solvent such as alcohol. Electrolytic oxidation causes the production of iodine, resulting in an immediate Karl Fischer reaction. Coulomteric Karl Fischer is used for moisture estimation in speciality chemicals, refrigerant gases, transformer & lubricant manufacturers, agrichemicals, pharmaceutical API & bulk drug.
| Product Code | Description | Pack Size |
|---|---|---|
| AXI | AQUAMICRON AXI | 500 ml |
| CXU | AQUAMICRON CXU | 10 x 5ml ampule/case |
| Product Code | Description | Pack Size |
|---|---|---|
| AXI | AQUAMICRON AXI | 500 ml |
Actylis Lab offers volumetric reagents and coulometric reagents. Our volumetric version uses anhydrous ingredients in a pyridine-free single solution. We also supply Aquamicron® coulometric reagents from Japan for trace moisture testing
Keep the reagent in a dry area. Store it in a cool place away from heat. Avoid direct sunlight. Use a sealed container to stop air from getting in. Use metal drums or fiberboard containers with a plastic lining. Keep the reagent away from moisture.
We use in-house R&D technology for stable volumetric reagents. Each batch is tested for factor consistency and viscosity. The Aquamicron reagents are backed by Mitsubishi Chemical and support ppm-level accuracy .
We provide 500 ml and 2×250 ml bottles for volumetric use. Coulometric reagents and water standards come in ampoules or bottles, depending on your needs Actylis Lab Solutions.
Yes. Our technical team helps you choose the right reagent and optimize methods. We also share protocols for volumetric and coulometric titrations .
Actylis Lab offers pyridine-free reagents, stable factor formulations, and trusted Aquamicron reagents. We ship quickly from India, provide full documentation (COA/MSDS), and support ppm-level moisture testing across industries .
